The mission of The Methodology Center is to advance public health by improving experimental design and data analysis in the social, behavioral, and health sciences.

Discovering Hidden Subgroups
Latent class analysis (LCA) allows researchers to detect the existence of subgroups within populations. Latent transition analysis (LTA) extends LCA to changes in group membership over time.
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Analyzing Rich, Complex Data Sets
Our intensive longitudinal data project provides tools for analyzing data with many observations, like data collected in smartphone studies. Our high-dimensional data project provides tools for variable selection and analysis of datasets with large numbers of variables, like genetics data.
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Designing and Building Health Interventions
The sequential, multiple assignment, randomized trial (SMART) project provides tools for building adaptive interventions so that treatments adapt to meet patients’ needs. The multiphase optimization strategy (MOST) is a framework for engineering interventions for purposes such as maximizing intervention potency within a specified cost limit or streamlining existing interventions for scale-up.
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Inferring Cause Without Randomization
Social, behavioral, and health researchers often face situations where randomization is not possible, practical, or ethical. Our causal inference project develops methods for inferring causality in non-randomized experiments or studies.
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The mission of The Methodology Center is to advance public health by improving experimental design and data analysis in the social, behavioral, and health sciences.
June 4, 2013
We are pleased to announce the release of the %FactorialPowerPlan SAS macro for planning a factorial or fractional factorial experiment. The calculations can be done for either posttest-only or pretest-posttest designs. Participants can either be assumed to be independent, or nested within existing clusters as discussed in Dziak, Nahum-Shani, and Collins (2012).
The macro can be used to calculate
May 15, 2013
It's been a good spring for Debashsis Ghosh, who has accepted an invitation to serve as chairperson of the Biostatistical Methods and Research Design Study Section at NIH's Center for Scientific Review for the next two years. Members of study sections are selected on the basis of their demonstrated competence and achievement in their scientific discipline as evidenced by the quality of research accomplishments, publications in scientific journals, and other significant scientific activities, achievements and honors. Membership on a study section represents a major commitment of professional time and energy as well as a unique opportunity to contribute to the national biomedical research effort. The skill and leadership offered by the chairperson is an important factor in the effectiveness and efficiency of the review group.

The Methodology Center will be active at the upcoming annual meeting of the Society for Prevention Research (SPR). At this year's conference, The Science of Prevention: Building a Comprehensive National Strategy for Well-Being, we will be presenting symposiums, a special interest group, paper talks, and multiple posters. Also look for us at the ECPN symposiums. We hope to see you there!
May 6, 2013
Debashis Ghosh has been awarded the 2013 Mortimer Spiegelman Award. The award was created in 1970 by the Applied Public Health Statistics Section of the American Public Health Association (APHA) to honor a statistician, 40 years of age or younger, who has made outstanding contributions to health statistics, especially public health statistics. The award is presented annually at the APHA meeting, and it serves three purposes: to honor the outstanding achievements of both the recipient and Spiegelman, to encourage further public health involvement by the finest young statisticians, and to increase awareness of APHA and the Applied Public Health Statistics Section in the academic statistical community. The award will be presented at the 2013 APHA meeting in November.



