Linda Collins, Ph.D.

Linda Collins, Ph.D.Director, The Methodology Center

Distinguished Professor, Department of Human Development and Family Studies

Professor, Department of Statistics

 

The Methodology Center

The Pennsylvania State University

204 E. Calder Way, Suite 400

State College, PA 16801

 

814-865-3253

CV

LinkedIn profile

 

 

Education

Ph.D., University of Southern California, 1983 (Quantitative Psychology)

B.A., University of Connecticut, 1977 (Psychology)

 

 

Research Interests

I am interested in most aspects of research methods. Lately I have been most interested in experimental and non-experimental design, particularly for building, optimizing and evaluating behavioral interventions. I also have a long-standing interest in models for longitudinal data, particularly latent transition analysis, and other latent class models.

 

 

Current Projects and Collaborators

I am working on two related projects to bring ideas from engineering to bear on optimization of behavioral interventions. My collaborators on these projects are Daniel E. Rivera (Arizona State University), Runze Li, Inbal Nahum-Shani (University of Michigan), John Dziak, and Susan Murphy. I also collaborate frequently with Stephanie Lanza on research related to latent class and latent transition analysis.

 

 

Honors and Awards

2011: Evan G. and Helen G. Pattishall Outstanding Research Achievement Award, Penn State College of Health and Human Development

2009-2011: President, Society for Prevention Research

2007-2009: President-Elect, Society for Prevention Research

2004: President’s Award, Society for Prevention Research

2000: Penn State Faculty Scholar Medal for the Social and Behavioral Sciences

1997-2004: Core Scientist for the Tobacco Etiology Research Network funded by the Robert Wood Johnson Foundation

1997: Elected Fellow, American Psychological Society

1996: Elected Fellow, Division 5, American Psychological Association

1995: President of Society of Multivariate Experimental Psychology

1992: USC Psychology Department Teacher of the Year

1991: R.B. Cattell Award for Distinguished Multivariate Behavioral Research

1991: USC Psychology Department Mentorship Award

1987: Elected to Society for Multivariate Experimental Psychology

Selected Grants

Current

Center for Prevention and Treatment Methodology

National Institute on Drug Abuse: P50 (Renewal)

2010-2015; Role: Principal Investigator

 

Engineering Effective Interventions for Tobacco Use: A Translational Laboratory 

National Cancer Institute: P01

2014-2019; Role: Principal Investigator of Core (Center Directors: Michael Fiore and Timothy Baker, University of Wisconsin)

 

Opt-In: Optimizing Intensive Intervention for Weight Loss

National Institute of Diabetes and Digestive and Kidney Diseases: R01

2011-2016; Role: Co-PI with Bonnie Spring

 

Previous

Dynamical Systems and Related Engineering Approaches to Improving Behavioral Interventions

National Institutes of Health Roadmap: R21

2007-2012; Role: Principal Investigator with Daniel Rivera

 

Center for Prevention and Treatment Methodology

National Institute on Drug Abuse: P50 (Renewal)

2005-2010; Role: Principal Investigator

 

Methodology for Drug Abuse Prevention Research

National Institute on Drug Abuse: K05

Role: Principal Investigator

 

Prevention and Methodology Training

National Institute on Drug Abuse: T32

2005-2010; Role: Investigator

 

 

 

 

Recent Teaching

Fall 2012: Quantitative Methods for Intervention Science. (HDFS 597D) Penn State Department of Human Development and Family Studies.

Fall 2013: Quantitative Methods for Intervention Science. (HDFS 597D) Penn State Department of Human Development and Family Studies.

 

 

Selected Recent Publications

Books and Monographs

Collins, L. M., & Lanza, S. T. (2010). Latent class and latent transition analysis: With applications in the social, behavioral, and health sciences. New York: Wiley.

 

Special Issues of Journals

Murphy, S. A., Collins, L. M., & Rush, A. J. (2007). Special issue of Drug and Alcohol Dependence: Customizing treatment to the patient: Adaptive treatment strategies. Elsevier.

 

Journal Articles and Book Chapters 

Collins, L. M., Dziak, J. D., Kugler, K. C., & Trail, J. B. (in press). Factorial experiments: Efficient tools for evaluation of intervention components. American Journal of Preventive Medicine. 

Pellegrini, C. A., Hoffman, S. A., Collins, L. M., & Spring, B. (2014). Optimization of remotely delivered intensive lifestyle treatment for obesity using the Multiphase Optimization Strategy: Opt-IN study protocol. Contemporary clinical trials.

Wyrick, D. L., Rulison, K. L., Fearnow -Kenney, M., Milroy, J. J., & Collins, L. M. (2014). Moving beyond the treatment package approach to developing behavioral interventions: Addressing questions that arose during an application of the multiphase optimization strategy (MOST). Translational Behavioral Medicine. Advance online publication. doi: 10.1007/s13142-013-0247-7 

Collins, L. M., Nahum-Shani, I., & Almirall, D. (2014). Optimization of behavioral dynamic treatment regimens based on the sequential, multiple assignment, randomized trial (SMART). Clinical Trials. doi: 10.1177/1740774514536795 

Timms, K. P., Rivera, D. E., Collins, L. M., & Piper, M. E. (2014). Continuous-time system identification of a smoking cessation intervention. International Journal of Control. Advance online publication. doi:10.1080/00207179.2013.874080

Timms, K. P., Rivera, D. E., Collins, L. M., & Piper, M. E. (2014).  A dynamical systems approach to understand self-regulation in smoking cessation behavior change. Nicotine and Tobacco Research, 16, S159-S168. doi: 10.1093/ntr/ntt149 PMCID: PMC3977628

Collins, L. M. (2013).  Optimizing family interventions: The Multiphase Optimization Strategy (MOST).  In McHale, S. McHale, P. Amato, P., & A. Booth, A. (Eds.). Emerging methods in family research. New York: Springer.

Lippold, M. A., Greenberg, M. T., & Collins, L. M. (2013).  Youths’ substance use and changes in parental knowledge-related behaviors during middle school: A person-oriented approach.  Journal of Youth and Adolescence. Advance online publication. doi: 10.1007/s10964-013-0010-x PMCID: PMC3938985

Collins, L., Trail, J., Kugler, K., Baker, T., Piper, M., & Mermelstein, R. (2013). Evaluating individual intervention components: making decisions based on the results of a factorial screening experiment. Translational Behavioral Medicine. Advance online publication. doi: 10.1007/s13142-013-0239-7 NIHMSID: NIHMS544386 

Collins, L. M., MacKinnon, D. P., & Reeve, B. (2013). Commentary: Some methodological considerations in theory-based health behavior research.  Health Psychology, 32, 586-591. PMCID: PMC3832141

Lippold, M. A., Greenberg, M. T., & Collins, L. M. (2013). Parental knowledge and youth risky behavior: A person oriented approach.  Journal of Youth and Adolescence. Advance online publication. doi: 10.1007/s10964-012-9893-1 PMCID: PMC3655137

Lanza, S. T., Bray, B. C., & Collins, L. M. (2013). An introduction to latent class and latent transition analysis. In J. A. Schinka, W. F. Velicer, & I. B. Weiner (Eds.), Handbook of psychology (2nd ed.,Vol. 2, pp. 691-716). Hoboken, NJ: Wiley.

Trail, J. B., Collins, L. M., Rivera, D. E., Li, R., Piper, M., & Baker, T. (2013).  Functional data analysis for the system identification of behavioral processes.  Psychological Methods. Advance online publication. doi: 10.1037/a0034035 PMC Journal-In Process

Timms, K. P., Rivera, D. E., Collins, L. M., & Piper, M. E. (2013).  Control systems engineering for understanding and optimizing smoking cessation interventions. Proceedings from the 2013 American Control Conference. 

Dziak, J., Nahum-Shani, I. R., Collins, L. M. (2012). Multilevel factorial experiments for developing behavioral interventions: Power, sample size, and resource considerations. Psychological Methods, 17, 153-175. Advance online publication. PMCID: PMC3351535

Piper, M. E., Baker, T. B., Mermelstein, R., Collins, L. M., Fraser, D., Jorenby, D. E., …, Fiore, M. C. (2012). Recruiting and engaging smokers in treatment in a primary care setting: Developing a chronic care model implemented through a modified electronic health record. Translational Behavioral Medicine, 3, 253-63. doi: 10.1007/s13142-012-0178-8 PMCID: PMC3771018

Thomas, D. M., Navarro-Barrientos, J. E., Rivera, D. E., Heymsfield, S. B., Bredlau, C., Redman, L. M., Martin, C. K., Lederman, S. A., Collins, L. M., & Butte, N. F. (2012). Dynamic energy-balance model predicting gestational weight gain. American Journal of Clinical Nutrition, 95, 115-122. PMCID: PMC3238455

Baker, T. B., Mermelstein, R. J., Collins, L. M., Piper, M. E., Jorenby, D. E., Smith, S. S., Schlam, T. R. Cook, J. W., & Fiore, M. C. (2011). New methods for tobacco dependence treatment research. Annals of Behavioral Medicine, 41, 192-207. PMCID: PMC3073306

Collins, L. M., Baker, T. B., Mermelstein, R. J., Piper, M. E., Jorenby, D. E., Smith, S. S., Schlam, T. R., Cook, J. W., & Fiore, M. C. (2011). The Multiphase Optimization Strategy for engineering effective tobacco use interventions. Annals of Behavioral Medicine, 41, 208-226. PMCID: PMC3053423

Caldwell, L. L., Smith, E. A., Collins, L. M., Graham, J. W., Lai, M., Wegner, L., Vergnani, T., Matthews, C., & Jacobs, J. (2012). Translational research in South Africa: Evaluating implementation quality using a factorial design. Child and Youth Care Forum, 41, 119-136. PMCID: PMC3375728

Graham, J. W., & Collins, L. M. (2012). Using modern missing data methods with auxiliary variables to mitigate the effects of attrition on statistical power. In Graham, J. W., Missing data: Analysis and design. New York: Springer.

Zafra-Cabeza, A., Rivera, D. E., Collins, L. M., Ridao, M. A., & Camacho, E. F. (2011). A risk-based model predictive control approach to adaptive interventions in behavioral health. IEEE Transactions on Control Systems Technology, 19, 891-901. PMCID: PMC3107527

Navarro-Barrientos, J.-E., Rivera, D. E., & Collins, L. M. (2011). A dynamical model for describing behavioural interventions for weight loss and body composition change. Mathematical and Computer Modelling of Dynamical Systems, 17, 183-203. PMCID: PMC3111923

Valentine, J. C., Biglan, A., Boruch, R. F., Castro, F.G., Collins, L. M., Flay, B. R., Kellam, S., Moscicki, E. K., & Schinke, S. (2011). Replication in Prevention Science. Prevention Science, 12, 103-117.

Tan, X., Dierker, L., Rose, J., Li, R., & Tobacco Etiology Research Network. (2011). How spacing of data collection may impact estimates of substance use. Substance Use and Misuse, 46, 758-768. PMCID: PMC3107528

Cleveland, M. J., Collins, L. M., Lanza, S. T., Greenberg, M. T., & Feinberg, M. E. (2010). Does individual risk moderate the effect of contextual-level protective factors? A latent class analysis of substance use. Journal of Prevention & Intervention in the Community, 38(3), 213-228. PMCID: PMC2898733

Lanza, S. T., & Collins, L. M. (2010). Modeling multidimensional sexual risk behavior using latent class analysis. In L. Passero, & C. Sgariglia (Eds.), Sexual Risk Behaviors (pp. 119-124). Hauppauge, NY: Nova Science Publishers Inc.

Bray, B. C., Lanza, S. T., & Collins, L. M. (2010). Modeling relations among discrete developmental processes: A general approach to associative latent transition analysis. Structural Equation Modeling, 17, 541-569. PMCID: PMC3094019

Collins, L. M., Chakraborty, B., Murphy, S. A., & Strecher, V. J. (2009). Comparison of a phased experimental approach and a single randomized clinical trial for developing multicomponent behavioral interventions. Clinical Trials, 6(1), 5-15. PMCID: PMC2711350

Patrick, M. E., Collins, L. M., Smith, E., Caldwell, L., Flisher, A., & Wegner, L. (2009). A prospective longitudinal model of substance use onset among South African adolescents. Substance Use & Misuse, 44(5), 647-662. PMCID: PMC2796627

Collins, L. M., Dziak, J. J., & Li, R. (2009). Design of experiments with multiple independent variables: A resource management perspective on complete and reduced factorial designs. Psychological Methods, 14(3), 202-224. PMCID: PMC2796056

Chakraborty, B., Collins, L. M., Strecher, V. J., & Murphy, S. A. (2009). Developing multicomponent interventions using fractional factorial designs. Statistics in Medicine, 28(21), 2687-2708. PMCID: PMC2746448

Dierker, L. C., Stolar, M., Richardson, E., Tiffany, S., Flay, B., Collins, L., Nichter, M., Nichter, M., Bailey, S., Clayton, R., & the Tobacco Etiology Research Network (TERN). (2008). Tobacco, alcohol and marijuana use among first year U.S. college students: A time series analysis. Substance Use and Misuse, 43, 680-699. PMCID: PMC2706584

Strecher, V. J., McClure, J. B., Alexander, G. W., Chakraborty, B., Nair, V. N., Konkel, J. M., Greene, S. M., Collins, L. M., Carlier, C. C., Wiese, C. J., Little, R. J., Pomerleau, C. S., & Pomerleau, O. F. (2008). Web-based smoking cessation programs: Results of a randomized trial. American Journal of Preventive Medicine, 34, 373-381. PMCID: PMC2697448

Lanza, S. T., & Collins, L. M. (2008). A new SAS procedure for latent transition analysis: Transitions in dating and sexual risk behavior. Developmental Psychology, 44(2), 446-456. PMCID: PMC2846549

 

Presentations

Collins, L. M. (November, 2013).  Raising the bar: Engineering optimized behavioral interventions for increased public health impact.  Presented at Presented at the Workshop on the Prevention of Obesity in Infancy and Early Childhood, Bethesda, MD.

Collins, L. M. (November, 2013). Unpacking the black box: Engineering more potent behavioral interventions using the Multiphase Optimization Strategy (MOST). Presented at the European Society for Prevention Research conference, Paris, France.

Collins, L. M. (September, 2013).  How optimizing behavioral interventions will help advance the national HIV/AIDS strategy.  Presented at The Future of HIV Prevention and Treatment:  Integrating Innovative Methods with Intervention Science, Bethesda, MD.

Collins, L. M. (September, 2013). Introduction to the Multiphase Optimization Strategy (MOST).  Presented at The Future of HIV Prevention and Treatment:  Integrating Innovative Methods with Intervention Science, Bethesda, MD.

Collins, L. M. (September, 2013).  Dynamic interventions:  Opportunities and challenges.  Presented at Big D.A.T.A. (Data And Theory Advancement) Workshop, Bethesda, MD.

Collins, L. M. (June, 2013). The Multiphase Optimization Strategy (MOST) for building more efficient and effective behavioral interventions.  Presented at the Osher Center for Integrative Medicine, University of California, San Francisco, CA.

Collins, L. M. (June, 2013). Unpacking the black box: Engineering more potent behavioral interventions using the Multiphase Optimization Strategy (MOST).  Presented at the MD Anderson Cancer Center, University of Texas, Houston, TX.

Collins, L. M. (May, 2013). Optimizing behavioral interventions: An integration of methodological perspectives from the behavioral and engineering sciences.  Presented at the Modern Modeling Methods Conference, University of Connecticut, Storrs, CT.

Collins, L. M., Nahum-Shani, I., & Almirall, D. (April, 2013).  SMART: An integral part of the Multiphase Optimization Strategy (MOST).  Presented at the 6th Annual Conference on Statistical Issues in Clinical Trials, University of Pennsylvania, Philadelphia, PA.

Collins, L. M. (March, 2013).  Raising the bar: Engineering optimized behavioral interventions for increased public health impact.  Presented at the Mind the Gap lecture series, National Institutes of Health, Bethesda, MD.

Collins, L. M. (2013, January). Unpacking the black box: Engineering more potent behavioral interventions using the Multiphase Optimization Strategy (MOST).  Presented at the BSRF Journal Club Series, University of Kentucky, Lexington, KY.

Collins, L. M. (2012, December). Improving intervention design and development: The Multiphase Optimization Strategy (MOST).  Presented at Physical Activity and Disease Prevention: Identifying Research Priorities, Office of Disease Prevention, National Institutes of Health, Bethesda, MD.

Collins, L. M. (2012, December).  Unpacking the black box: The Multiphase Optimization Strategy (MOST) for building more potent behavioral interventions.  Presented at the Wednesday Workshop Series, Institute for Public Health and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.

Almirall, D., Collins, L. M., & Murphy, S. A. (2012, November). Getting SMART about the design of experimental trials for the development of adaptive health interventions. Presented at the second Innovative Methods Program for Advancing Clinical Trials, Raleigh, NC.

Collins, L. M. (2012, October). Optimizing family intervention programs: The multiphase optimization strategy.  Presented at the 20th Annual Penn State Symposium on Family Issues, University Park, PA.

Collins, L. M. (2012, October). Unpacking the black box: Engineering more potent preventive interventions using the Multiphase Optimization Strategy (MOST).  Presented at the Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse, Bethesda, MD.

Collins, L. M., Caldwell, L. L., Smith, E. A., Graham, J. W., Lai, M., Wegner, L., …, & Jacobs, J.  (2012, September).  Implementation fidelity in a drug abuse and HIV prevention program in South Africa: Taking an experimental approach to establish what works.  Presented at the International Congress of Behavioral Medicine, Budapest, Hungary.

Collins, L. M. (2012, July). Integrating ideas from statistics and engineering into behavioral intervention science. Presented at the Guanghua School of Management, Peking University, Beijing, China.

Collins, L. M., Dziak, J. J., & Nahum-Shani, I. (2012, July). Fractional factorial experiments and cluster randomization: An integration of engineering research methods and educational research methods. Presented at the Institute of Mathematical Statistics Asia-Pacific Rim Meeting, Tskuba, Japan.

Trail, J. B., Collins, L. M., Rivera, D. E., Li, R., & Piper, M. E. (2012, July). A dynamical systems approach for adaptive intervention development. Presented at the Institute of Mathematical Statistics – Asia Pacific Rim Meeting, Tsukuba, Japan.

Collins, L. M. (2012, June). The multiphase optimization strategy (MOST) for engineering better behavioral and educational interventions. Presented at the Institute for Policy Research, Northwestern University, Evanston, IL.

Kugler, K. C., Collins, L. M., & Wyrick, D. (2012, June). Improving Behavioral Interventions via the Multiphase Optimization Strategy (MOST). Paper presented at the Society of Epidemiologic Research Annual Meeting, Minneapolis, Minnesota.

Collins, L. M. (2012, June). Introduction to the multiphase optimization strategy (MOST). In Alcohol and drug prevention for student-athletes: An application of the multiphase optimization strategy (MOST) in a multilevel setting. Presented at the 20th Annual Meeting of the Society for Prevention Research, Washington, DC.

Collins, L. M., & Dierker, L. C. (2012, June). Innovative systems science methods for the design and evaluation of adaptive behavioral interventions. In Collins, L. M. (Chair), Building Optimized Prevention Interventions. Special Interest Group. Presented at the 20th Annual Meeting of the Society for Prevention Research, Washington, DC.

Dziak, J. J., Nahum-Shani, I., & Collins, L. M. (2012, June). Multilevel factorial experiments for developing behavioral interventions. In Alcohol and drug prevention for student-athletes: An application of the multiphase optimization strategy (MOST) in a multilevel setting. Presented at the 20th Annual Meeting of the Society for Prevention Research, Washington, DC.

Kugler, K. C., Collins, L. M., & Trail, J. (2012, June). Effect coding and dummy coding in analysis of variance: They are not always the same. Poster presented at the 20th Annual Meeting of the Society for Prevention Research, Washington, DC.

Trail, J. B., Collins, L. M., Rivera, D. E., Li, R., & Piper, M. E. (2012, June). A dynamical systems approach for adaptive intervention development. In Collins, L. M. (Chair), Building Optimized Prevention Interventions. Special Interest Group. Presented at the 20th Annual Meeting of the Society for Prevention Research, Washington, DC.

Collins, L. M. (2012, April). Introduction to the multiphase optimization strategy (MOST) for building more effective behavioral interventions. Preconference workshop presented at The Annual Meeting of the Society for Behavioral Medicine, New Orleans, LA..

Kugler, K. C., & Collins, L. M. (2012, April). Improving behavioral interventions via the multiphase optimization strategy (MOST). Presented at The Annual Meeting of the Society for Behavioral Medicine, New Orleans, LA.

Kugler, K. C., Trail, J., & Collins, L. M. (2012, April). Effect coding and dummy coding in analysis of variance: They are not always the same. Poster presented at The Annual Meeting of the Society for Behavioral Medicine, New Orleans, LA.

Trail, J. B., Piper, M. E., Collins, L. M., & Rivera, D. E. (2012, April). Dynamical systems analysis of smoking cessation data. Poster presented at The Annual Meeting of the Society for Behavioral Medicine, New Orleans, LA.

Collins, L. M. (2012, March). The multiphase optimization strategy (MOST) for engineering better behavioral interventions. Presented at MDRC, New York, NY.

Collins, L. M. (2012, March). Unpacking the black box: Engineering more potent behavioral interventions to improve public health. Annual Pattishall Lecture. Presented at the College of Health and Human Development, Penn State, University Park, PA.

Trail, J. B., Collins, L. M., Rivera, D. E., Li, R., & Piper, M. E. (2012, March). A dynamical systems analysis of smoking cessation data. Poster presented at The Annual Meeting of the Society for Research on Nicotine and Tobacco, Houston, TX.

Collins, L. M., & Lanza, S. T. (2012, February). Latent class analysis. Workshop presented for Methods Work, Pittsburgh, PA. Also presented October, 2011 for Methods Work, Washington, DC and August, 2011 for Methods Work, Atlanta, GA.

Collins, L. M. (2011, December). The Multiphase Optimization Strategy (MOST) for engineering better behavioral interventions. Invited talk presented at the Center for Technology and Behavioral Health, Dartmouth Psychiatric Research Center, Dartmouth University.

Collins, L. M. (2011, June). Prevention in the 21st Century: Adapting engineering optimization strategies to create leaner, meaner, better interventions. Presidential address presented at the Society for Prevention Research Annual Meetings, Washington, DC.

Trail, J., Timms, K., Piper, M. E., Rivera, D., & Collins, L. M. (2011, June). Functional data analysis of smoking cessation data. Poster presented at the Society for Prevention Research Annual Meetings, Washington, DC.

Trail, J. B., Timms, K., Piper, M., Collins, L. M., & Rivera, D. E. (2011, May). Dynamic mediation analysis of intensive longitudinal data. Poster presented at the Modern Modeling Methods Conference, Storrs, CT.

Collins, L. M. (2011, April). Drawing on ideas from engineering and computer science to build better behavioral interventions. Symposium presented at the Society of Behavioral Medicine Annual Meeting & Scientific Sessions, Washington, DC.

Collins, L. M. (2011, April). Efficient designs for examining the effects of individual intervention components. In From discovery to public health impact: New approaches to developing, testing, and optimizing behavioral interventions. Preconference workshop presented at the Society of Behavioral Medicine Annual Meeting & Scientific Sessions, Washington, DC.

Collins, L. M. (2011, April). Introduction to the multiphase optimization strategy (MOST) for building more effective behavioral interventions. Seminar presented at the Society of Behavioral Medicine Annual Meeting & Scientific Sessions, Washington, DC.

Collins, L. M., Dziak, J. J., & Nahum-Shani, I. (2011, April). Factorial experimental designs in multilevel situations. In L. M. Collins (Chair), Drawing on ideas from engineering and computer science to build better behavioral interventions. Symposium presented at the Society of Behavioral Medicine Annual Meeting & Scientific Sessions, Washington, DC.

Collins, L. M. (2011, February) Blending psychology and engineering to build better behavioral interventions. Presented at the Psychology: Transforming Science and Practice (50th Anniversary Celebration for URI Department of Psychology), University of Rhode Island, Kingston, RI.

Collins, L. M. (2011, January) The multiphase optimization strategy (MOST) for engineering better behavioral interventions. Presented at the the Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL.

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